Publications

2018

Edith Bonnin, Pauline Cabochette, Alessandro Filosa, Ramona Jühlen, Shoko Komatsuzaki, Mohammed Hezwani, Achim Dickmanns, Valérie Martinelli, Marjorie Vermeersch, Lynn Supply, Nuno Martins, Laurence Pirenne, Gianina Ravenscroft, Marcus Lombard, Sarah A. Port, Christiane Spillner, Sandra Janssens, Ellen Roets, Jo Van Dorpe, Martin Lammens, Ralph H. Kehlenbach, Ralf Ficner, Nigel G. Laing, Katrin Hoffmann, Benoit Vanhollebeke, and Birthe Fahrenkrog (2018) Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence. PLoS Genet. 14: e1007845.


Birthe Fahrenkrog and Amnon Harel (2018) Perturbations in traffic: Aberrant nucleocytoplasmic transport at the heart of 

neurodegenerationCells 7: pii:E232.


Ramona Jühlen and Birthe Fahrenkrog (2018) Moonlightning nucleoporins: tissue-specific nucleoporin function in health and disease. Histochem. Cell. Biol. 150:593-605.


Muhammad Shoaib, David Walter, Peter J Gillespie, Fanny Izard, Birthe Fahrenkrog, David Llerer, Mads Lerdrup, Jens Vilstrup Johansen, Klaus Hansen, Eric Julien, J. Julian Blow, and Claus S. Sorensen (2018) A histone H4K20 methylation-mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing. Nat. Commun. 9: 3704.


Nuno Martins, Adelia Mendes, and Birthe Fahrenkrog (2018) On the effects of leukemogenic nucleoporin fusion proteins on nucleocytoplasmic transport and gene expression. Nuclear-Cytoplasmic Transport, Nucleic Acids and Molecular Biology, 33, https://doi.org/10.1007.978-3-319-77309-4_10


Didac Carmona-Gutierrez, Maria Anna Bauer, Andreas Zimmermann, Andrés Aguilera, Nicanor Austriaco, Kathryn Ayscough, Rena Balzan, Shoshana Bar-Nun, Antonio Barrientos, Peter Belenky, Marc Blondel, Ralf J. Braun, Michael Breitenbach, William C. Burhans, Sabrina Büttner, Duccio Cavalieri, Michael Chang, Katrina F. Cooper, Manuela Côrte-Real, Vítor Costa, Christophe Cullin, Ian Dawes, Jörn Dengjel, Martin B. Dickman, Tobias Eisenberg, Birthe Fahrenkrog, Nicolas Fasel, Kai-Uwe Fröhlich, Ali Gargouri, Sergio Giannattasio, Paola Goffrini, Campbell W. Gourlay, Chris M. Grant, Michael T. Greenwood, Nicoletta Guaragnella, Thomas Heger, Jürgen Heinisch, Eva Herker, Johannes M. Herrmann, Sebastian Hofer, Antonio Jiménez-Ruiz, Helmut Jungwirth, Katharina Kainz, Dimitrios P. Kontoyiannis, Paula Ludovico, Stéphen Manon, Enzo Martegani, Cristina Mazzoni, Lynn A. Megeney, Chris Meisinger, Jens Nielsen, Thomas Nyström, Heinz D. Osiewacz, Tiago F. Outeiro, Hay-Oak Park, Tobias Pendl, Dina Petranovic, Stephane Picot, Peter Polčic, Ted Powers, Mark Ramsdale, Mark Rinnerthaler, Patrick Rockenfeller, Christoph Ruckenstuhl, Raffael Schaffrath, Maria Segovia, Fedor F. Severin, Amir Sharon, Stephan J. Sigrist, Cornelia Sommer-Ruck, Maria João Sousa, Johan M. Thevelein, Karin Thevissen, Vladimir Titorenko, Michel B. Toledano, Mick Tuite, F.-Nora Vögtle, Benedikt Westermann, Joris Winderickx, Silke Wissing, Stefan Wölfl, Zhaojie J. Zhang, Richard Y. Zhao, Bing Zhou, Lorenzo Galluzzi, Guido Kroemer, and Frank Madeo (2018) Guidelines and recommendations on yeast cell death nomenclature. Microbial Cell 5: 4-31.


2017

Mohammed Hezwani and Birthe Fahrenkrog (2017) The Functional Versatility of The Nuclear Pore Complex Proteins. Sem. Cell Dev. Biol. 68: 2-9.


Nadine Nilles and Birthe Fahrenkrog (2017) Taking a bad turn: DNA double strand break repair in leukemia. Cells 6: pii:E11.


Vincent Duheron, Nadine Nilles, Sylvia Pecenko, Valérie Martinelli, and Birthe Fahrenkrog (2017) Localization of nucleoporin Nup153 and SUMO isopeptidase SENP1 to nuclear pore complexes is required for 53BP1 function in DNA double-strand break repair. J. Cell Sci. 130: 2306-2316.


2016

Sarah A. Port, Adélia Mendes, Christina Valkova, Christiane Spillner, Birthe Fahrenkrog, Christoph Kaether, and Ralph H. Kehlenbach (2016) The oncogenic fusion proteins SET-Nup214 and sequestosome-1 (SQSTM1)-Nup214 form dynamic nuclear bodies and differentially affect nuclear protein- and mRNA export. J. Biol. Chem. 291: 23068-23083.


Birthe Fahrenkrog, Valérie Martinelli, Nadine Nilles, Gernot Fruhmann, Guillaume Chatel, Sabine Juge, Ursula Sauder, Darai Di Giacome, Christina Mecucci, and Jürg Schwaller (2016) Expression of leukemia-associated Nup98 fusion proteins generates an aberrant nuclear envelope phenotype. PLOS One 11: e0152321.


Birthe Fahrenkrog (2016) Histone modifications as regulators of life and death in Saccharomyces cerevisiae. Microbial Cell 3: 1-13.


2015

Ikram Mossaid and Birthe Fahrenkrog (2015) Complex commingling: nucleoporins and the spindle assembly checkpoint. Cells 4: 706-725.


Achim Dickmanns, Ralph H. Kehlenbach, and Birthe Fahrenkrog (2015) Nuclear pore complexes and nucleocytoplasmic transport: from structure to function to disease. Int. Rev. Cell Mol. Biol. 320: 171-233.


2014

Vincent Duheron, Guillaume Chatel, Ursula Sauder, Vesna Oliveri, and Birthe Fahrenkrog (2014) Structural characterization of altered nucleoporin Nup153 expression in human cells by thin-section electron microscopy. Nucleus 5: 601-612.


David Walter, Anja Matter, and Birthe Fahrenkrog (2014) Loss of histone H3 methylation at lysine 4 triggers apoptosis in S. cerevisiae. PLoS Genetics 10: e1004095.


Vincent Duheron and Birthe Fahrenkrog (2014) Nuclear pore complex: structure and function. Atlas Genet Cytogenet Oncol Haematol., http://atlasgeneticsoncology.org/Deep/NuclearPoreFunctionID20139.html.


Birthe Fahrenkrog (2014) Nucleoporin gene fusions and hematopoietic malignancies. New Journal of Science, Article ID 468306, 1-18. 


Nelly Panté and Birthe Fahrenkrog (2014) Exploring nuclear pore complex molecular architecture by immuno-electron microscopy using Xenopus oocytes. Methods Cell Biol. 122: 81-98.


2012

Sarah Derde, Ilse Vanhorebeek, Fabian Güiza, Inge Derese, Birthe Fahrenkrog, Wim Martinet, Hilke Vervenne, Eric-Jan Ververs, Lars Larsson, and Greet Van den Berghe (2012) Early parenteral nutrition evokes a phenotype of autophagy-deficiency in liver and skeletal muscle of critically ill rabbits. Endocrinology 153: 2267-2276.


Guillaume Chatel, Sachin H. Dessai, Alexa L. Mattheyses, Maureen A. Powers, and Birthe Fahrenkrog (2012) Domain topology of nucleoporin Nup98 within the nuclear pore complex. J. Struct. Biol. 177: 81-89.


Guillaume Chatel and Birthe Fahrenkrog (2012) Dynamics and Diverse Functions of nuclear pore complex proteins. Nucleus 3: 162-171.


2011

Birthe Fahrenkrog (2011) Nma111p, the pro-apoptotic HtrA-like nuclear serine protease in S. cerevisiae: a short survey. Biochem. Soc. Transactions 39: 1499-1501.


Guillaume Chatel and Birthe Fahrenkrog (2011) Nucleoporins: leaving the nuclear pore complex for a successful mitosis. Cell. Signal. 23: 1555-1562.


Teiba Al-Haboubi, Dale K. Shumaker, Joachim Köser, Manfred Wehnert and Birthe Fahrenkrog (2011) Distinct association of the nuclear pore protein Nup153 with A- and B-type lamins. Nucleus 2: 500-509.


Yvonne C. Lussi, Ilona Hügi, Eva Laurell, Ulrike Kutay, and Birthe Fahrenkrog (2011) Direct association of the nucleoporin Nup88 with the intermediate filament protein lamin A. Mol. Biol. Cell 22: 1080-1090.


2010

David Walter, Anja Matter, and Birthe Fahrenkrog (2010) Bre1p mediated histone H2B ubiquitination regulates metacaspase-dependent apoptosis in S. cerevisiae. J. Cell Sci. 123: 1931-1939.


Yvonne C. Lussi, Dale K. Shumaker, Takeshi Shimi, and Birthe Fahrenkrog (2010) The nucleoporin Nup153 is implicated in spindle checkpoint regulation due to its association with Mad1. Nucleus 1: 71-84.


Ales Obrdlik, Emilie Louver,  Alexander Kukalev,  Dmitri Naschekin, Elena Kiseleva, Birthe Fahrenkrog, and Piergiorgio Percipalle (2010) Nuclear myosin 1 is required for post-transcriptional control of rRNA biogenesis. FACEB J. 24: 146-157.


2009

Kenneth D. Belanger, David Walter, Tracey A. Perazone, Allison L. Yelton, Travis G. O’Brien, Karyn G. Belanger, Susan J. Geier, and Birthe Fahrenkrog (2009) Nuclear localization is critical for the proapoptotic activity of the HtrA-like serine protease Nma111p. J. Cell Sci. 122: 3931-3941.


Tobias Eisenberg, Heide Knauer, Alexandra Schauer, Sabrina Büttner, Christoph Ruckenstuhl, Didac Carmona-Gutierrez, Julia Ring, Sabrina Schroeder, Christoph Magnes, Lucia Antonacci, Heike Fussi, Luiza Deszcz, Regina Hartl, Elisabeth Schraml, Alfredo Criollo, Evgenia Megalou, Daniela Weiskopf, Peter Laun, Gino Heeren, Michael Breitenbach, Beatrix Grubeck-Loebenstein, Eva Herker, Birthe Fahrenkrog, Kai-Uwe Fröhlich, Frank Sinner, Nektarios Tavernarakis, Nadege Minois, Guido Kroemer and Frank Madeo (2009) Induction of autophagy by spermidine promotes longevity. Nature Cell Biol. 11: 1305-1314.


Yvonne Lussi and Birthe Fahrenkrog (2009) Nuclear pore complex organization and nucleoporin functions. Nuclear transport, Landes Bioscience, 19-37.


2008

Esther Owsianowski, David Walter, and Birthe Fahrenkrog (2008) Negative regulation of apoptosis in yeast. BBA Mol. Cell Res. 1783: 1303-1310.


Roderick Y.H. Lim, Katharine S. Ullman, and Birthe Fahrenkrog (2008) Biology and biophysics of the nuclear pore complex and its components. Int. Rev. Cell Mol. Biol. 267: 299-342.


Sara M. Paulillo, and Birthe Fahrenkrog (2008) The nuclear pore complex: from higher eukaryotes to plants. Current Research in Plant Cell Compartments, Selected Topics 1-17. 


Roderick Y.H. Lim, Ueli Aebi, and Birthe Fahrenkrog (2008) Towards reconciling structure and function of the nuclear pore complex. Histochem. Cell Biol. 129: 105-116.


2007

Roderick Y.H. Lim, Birthe Fahrenkrog, Joachim Köser, Kyrill Schwarz-Herion, Jie Deng, and Ueli Aebi (2007) Nanomechanical selective gating in the nuclear pore complex. Science 318: 640-643.


Kyrill Schwarz-Herion, Bohumil Maco, Ursula Sauder, and Birthe Fahrenkrog (2007)  Domain topology of the p62 complex within the 3-D architecture of the nuclear pore complex. J. Mol. Biol. 370: 796-806.


2006

Sara M. Paulillo, Maureen A. Powers, Katharine S. Ullman, and Birthe Fahrenkrog (2006) Changes in nucleoporin domain topology in response to chemical effectors. J. Mol. Biol. 363: 39-50.


Yoriko Lill, Markus A. Lill, Birthe Fahrenkrog, Kyrill Schwarz-Herion, Sara M. Paulillo, Ueli Aebi,  and Bert Hecht (2006) Single Hepatitis-B virus capsid binding to nuclear pore complexes in HeLa cells. Biophysical J. 91: 3123-3130.


Roderick Y.H. Lim, Ningping Huang, Joachim Köser, Jie Deng, Aaron K.H. Lau, Kyrill Schwarz-Herion, Birthe Fahrenkrog, and Ueli Aebi (2006) Flexible nucleoporins as entropic barriers to nucleocytoplasmic transport. Proc. Natl. Acad. Sci USA 103: 9512-9517.  


Daniel Stoffler, Kyrill Schwarz-Herion, Ueli Aebi, and Birthe Fahrenkrog (2006) Getting across the nuclear pore complex: new insights into nucleocytoplasmic transport. Can. J. Physiol. Pharmacol. 84: 499-507. 


David Walter, Silke Wissing, Frank Madeo, and Birthe Fahrenkrog (2006) The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast orthologue of Omi/HtrA2. J. Cell Sci. 119: 1843-1851.


Birthe Fahrenkrog, and Ueli Aebi (2006) The nuclear pore complex. Encyclopedic References of Genomics and Proteomics in Molecular Medicine, Part 14, doi:10.1007/3-540-29623-9_3000.


Birthe Fahrenkrog (2006) The nuclear pore complex, nuclear transport and apoptosis. Can. J. Physiol. Pharmacol. 84: 279-286. 

                                                                       

Roderick, Y.H. Lim, and Birthe Fahrenkrog (2006) The nuclear pore complex up close. Curr. Opin. Cell Biol. 18: 342-347.


2005

Sara M. Paulillo, Erica M. Phillips, Joachim Köser, Ursula Sauder, Katharine S. Ullman, Maureen A. Powers, and Birthe Fahrenkrog (2005) Nucleoporin domain topology is linked to the transport status of the nuclear pore complex. J. Mol. Biol. 351: 784-798.


Thorsten Libotte, Hafida Zaim, Sabu Abraham, V.C. Padmakumar, Maria Schneider, Wenshu Lu, Martina Munck, Christopher Hutchison, Manfred Wehnert, Birthe Fahrenkrog, Ursula Sauder, Ueli Aebi, Angelika A. Noegel, and Iakowos Karakesisoglou (2005) Lamin A/C dependent localization of the largest nesprin-2 isoform NUANCE, a giant scaffolder at the nuclear envelope. Mol. Biol. Cell 16: 3411-3424.


Bohumil Maco, Birthe Fahrenkrog, Ningping Huang, and Ueli Aebi (2005) Ultrastructure of the nuclear pore complex (NPC) revealed by electron and atomic force microscopy. Methods Mol. Biol. 322: 273-288.


Birthe Fahrenkrog (2005) The nuclear pore complex: Multifaceted and full of suspense. Zellbiologie aktuell 2: 18-20.


Joachim Köser, Bohumil Maco, Ueli Aebi, and Birthe Fahrenkrog (2005) The nuclear pore complex becomes alive: new insights into its dynamics and involvement in different cellular processes. Atlas Genet Cytogenet Oncol Haematol. February 2005. http://www.infobiogen.fr/services/chromcancer/Deep/NuclearPoreComplID20048.html.


2004

Kenneth D. Belanger, Laura Simmons, Jessica K. Roth, Kristin A. van der Ploeg, Laura Lichten, Laura I. Davis, and Birthe Fahrenkrog (2004) Nup82 is important for the translocation of distinct import and export substrates through the nuclear pore complex. J. Biol. Chem. 279: 43530-43539.


Birthe Fahrenkrog, Ursula Sauder, and Ueli Aebi (2004) The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J. Cell Sci. 117: 115-126.


Birthe Fahrenkrog, Joachim Köser, and Ueli Aebi (2004) The nuclear pore complex: a jack of all trades? Trends Biochem. Sci. 29: 175-182.


2003

Daniel Stoffler, Bernd Feja, Birthe Fahrenkrog, Jochen Walz, Dieter Typke, and Ueli Aebi (2003) Cryo-electron tomography provides novel insights into nuclear pore complex architecture - implications for nucleocytoplasmic transport. J. Mol. Biol. 328: 119-130.


Elissa P. Lei, Claudia A. Stern, Birthe Fahrenkrog, Heike Krebber, Terence I. Moy, Ueli Aebi, and Pamela A. Silver (2003) Sac3 is an mRNA export factor that localizes to the cytoplasmic fibrils of the nuclear pore complex. Mol. Biol. Cell 14: 836-847.


Birthe Fahrenkrog and Ueli Aebi (2003) The nuclear pore complex: nucleocytoplasmic transport and beyond. Nature Rev. Mol. Cell. Biol. 4: 757-766.


Birthe Fahrenkrog and Ueli Aebi (2003) Der Kernporenkomplex: Von der Struktur zur Funktion. Biospektrum 1/03: 27-30


2002

Birthe Fahrenkrog, Bohumil Maco, Ammon M. Fager, Joachim Köser, Ursula Sauder, Katharine S. Ullman, and Ueli Aebi. (2002) Domain specific antibodies reveal multiple-site topology of Nup153 within the nuclear pore complex. J. Struct. Biol. 140: 254-267.


Cora-Ann Schoenenberger, Nicolas Bischler, Birthe Fahrenkrog, and Ueli Aebi (2002) About actin’s propensity for dynamic filament patterning. FEBS Letters 529: 27-33.


Birthe Fahrenkrog, and Ueli Aebi (2002) The vertebrate nuclear pore complex: from structure to function. Res. Probl. Cell Diff. 35: 25-48.


2001

Birthe Fahrenkrog, Daniel Stoffler, and Ueli Aebi (2001) Nuclear pore complex architecture and functional dynamics. Curr. Top. Microbiol. Immunol. 259: 95-117.


2000

Birthe Fahrenkrog, Wolfgang Hübner, Anna Mandinova, Nelly Panté, Walter Keller, and Ueli Aebi (2000) The yeast nucleoporin Nup53p specifically interacts with Nic96p and is involved in nuclear protein import. Mol. Biol. Cell 11: 3885-3896.


Birthe Fahrenkrog, John P. Aris, Eduard C. Hurt, Nelly Panté, and Ueli Aebi (2000) Comparative localization of protein A tagged and endogenous yeast nuclear pore complex proteins by immunoelectron microscopy. J. Struct. Biol. 129: 295-305.


1999

Yvan Strahm, Birthe Fahrenkrog, Daniel Zenklusen, Elizabeth Rychner, Julia Kantor, Michael Rosbach, and Françoise Stutz (1999) The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p/Dbp5p and a new protein Ymr255p. EMBO J. 18: 5761-5777. 


Daniel Stoffler, Birthe Fahrenkrog, and Ueli Aebi (1999) The nuclear pore complex: From molecular architecture to functional dynamics. Curr. Opin. Cell Biol. 11: 391-401. 


1998

Helena Santos-Rosa, Horacio Moreno, George Simos, Alexandra Segref, Birthe Fahrenkrog, Nelly Panté, and Ed Hurt (1998) Nuclear mRNA export requires formation between Mex67p and Mtr2p at the nuclear pores. Mol. Cell. Biol. 18: 6826-6838.


Birthe Fahrenkrog, Eduard C. Hurt, Ueli Aebi, and Nelly Panté (1998) Molecular architecture of the yeast nuclear pore complex: Localization of Nsp1p subcomplexes. J. Cell Biol. 143: 577-588.



© Biology of the Nucleus 2019